Newest Review - published online ahead of print.

Everything you wanted to know about the SARS-CoV-2 E-Protein, which makes beautiful fivefold channels and is responsible for the curvature of virion particles - published ahead of print: https://doi.org/10.1080/0889311X.2023.2253735

Top view of the pentameric SARS-CoV-1 E-protein assembly with the ion channel at the centre (PDB: 5X29). Positively charged residues on the outside of the central helices interact with the negatively charged membrane lipids to anchor the pore. Figure was created using Protein Imager and PyMOL.