Publications

  1. Thorn A: Artificial Intelligence (AI) Methodologies in Structural Biology. Current Opinion in Structural Biology. 2021. [invited; in preparation]
  2. Macias JR, Sanchez-Garcia R, Conesa P, Ramirez-Aportela E, Martinez Gonzalez M, Wert-Carvajal C, Segura Mora J, Horrell S, Thorn A, Sorzano COS, Carazo JM: 3DBionotes COVID-19 Edition. Bioinformatics. 2021. doi: 10.1093/bioinformatics/btab397.
  3. Croll TI, Diederichs K, Fischer F, Fyfe CD, Gao Y, Horrell S, Joseph AP, Kandler L, Kippes O, Kirsten F, Müller K, Nolte K, Payne AM, Reeves MG, Richardson JS, Santoni G, Stäb S, Tronrud DE, von Soosten LC, Williams CJ, Thorn A: Making the invisible enemy visible. Nature Structural & Molecular Biology 28, 404–408 (2021). doi:10.1038/s41594-021-00593-7.
  4. Mostosi P, Schindelin H, Kollmannsberger P, Thorn A: Haruspex: A Neural Network for the Automatic Identification of Oligonucleotides and Protein Secondary Structure in Cryo‐Electron Microscopy Maps. Angewandte Chemie (International Edition) 59, 14788–14795 (2020). doi:10.1002/anie.202000421.
  5. Thorn A, Parkhurst JM, Emsley P, Nicholls RA, Evans G, Vollmar M, Murshudov GN: AUSPEX: a graphical tool for X-ray diffraction data analysis. Acta Crystallographica Section D, Structural Biology 73, 729–737 (2017). doi:10.1107/S205979831700969X.
  6. Parkhurst JM, Thorn A, Vollmar M, Winter G, Waterman DG, Fuentes-Montero L, Gildea RJ, Murshudov GN, Evans G: Background modelling of diffraction data in the presence of ice-rings. International Union of Crystallography Journal 4, 626–638 (2017). doi:10.1107/S2052252517010259.
  7. Thorn A: Experimental Phasing: Substructure Solution and Density Modification as Implemented in SHELX in Protein Crystallography. Methods in Molecular Biology (series), 357–376. Invited book chapter. Co-editors: Wlodawer A, Dauter Z, Jaskolski M, Springer 2017. doi:10.1007/978-1-4939-7000-1_15.
  8. Knott GJ, Panjikar S, Thorn A, Fox AH, Conte MR, Lee M, Bond CS: A crystallographic study of human NONO (p54nrb): Overcoming pathological problems with purification, data collection and non-crystallographic symmetry. Acta Crystallographica Section D, Structural Biology 72, 761–769 (2017). doi:10.1107/S2059798316005830.
  9. Deigan Warner K, Chen MC, Song W, Strack RL, Thorn A, Jaffrey SR, Ferré-D’Amaré AR: Structural basis for activity of highly efficient RNA mimics of green fluorescent protein, NSMB 21, 658–663 (2014). doi:10.1038/nsmb.2865.
  10. Thorn A, Sheldrick GM: Extending Molecular Replacement Solutions with SHELXE, Acta Crystallographica Section D, Structural Biology 69, 2251–2256 (2013). doi:10.1107/S0907444913027534.
  11. Cooper RI, Thorn A, Watkin DJ: CRYSTALS enhancements: asymmetric restraints. Journal of Applied Crystallography 45, 1057–1060 (2012). doi:10.1107/S0021889812035790.
  12. Thorn A, Steinfeld R, Ziegenbein M, Grapp M, Hsiao HH, Urlaub H, Sheldrick GM, Gärtner J, Krätzner R: Structure and activity of the only human RNase T2, Nucleic Acids Research 40, 8733–8742 (2012). doi:10.1093/nar/gks614.
  13. Thorn A, Dittrich B, Sheldrick GM: Enhanced rigid-bond restraints. Acta Crystallographica Section A, Foundations and Advances 68, 448–451 (2012). doi:10.1107/S0108767312014535.
  14. Thorn A, Sheldrick GM: ANODE: anomalous and heavy-atom density calculation. Journal of Applied Crystallography 44, 1285–1287 (2011). doi:10.1107/S0021889811041768.
  15. Vouffo B, Dongo E, Facey P, Thorn A, Sheldrick GM, Maier A, Fiebig HH, Laatsch H: Antiarol cinnamate and Africanoside, a cinnamoyl triterpene and a hydroperoxy-cardenolide from the stem bark of Antiaris Africana. Planta medica 76, 1717–1723 (2010). doi:10.1055/s-0030-1249958.
  16. Tavcar G, Sen SS, Azhakar R, Thorn A, Roesky HW: Facile syntheses of silylene nickel carbonyl complexes from Lewis base stabilized chlorosilylenes. Inorganic Chemistry 49, 10199–10202 (2010). doi:10.1021/ic101556s.
  17. Fischer A, Stern D, Thorn A, Abraham S, Stalke D, Klingebiel U: From the Lithium-2-anilide-2-fluoro-1,3-diaza-2-sila-cyclopentene-GaCl3 Adduct to 1,4,6-Triaza-5-gallium-7-sila-cyclo-3-heptene—Experimental and Quantum-chemical Results. Zeitschrift für Anorganische und Allgemeine Chemie 636, 1527–1532 (2010). doi:10.1002/zaac.201000041.
  18. Vollmar D, Thorn A, Schuberth I, Grond S: A comprehensive view on 4-methyl-2-quinazolinamine, a new microbial alkaloid from Streptomyces of TCM plant origin. Journal of Antibiotics 62, 439–444 (2009). doi:10.1038/ja.2009.68.
  19. Thorn A, Egerer-Sieber C, Jäger CM, Herl V, Müller-Uri F, Kreis W, Muller YA: The crystal structure of 5β-Progesterone Reductase from Digitalis Lanata defines of a novel subfamily of short-chain dehydrogenases/reductases. Journal of Biological Chemistry 283, 17260-17269 (2008). doi:10.1074/jbc.M706185200.
  20. Tampier S, Müller R, Thorn A, Hübner E, Burzlaff N: Synthesis, Structure and Reactivity of Ruthenium Carboxylato and 2-Oxocarboxylato Complexes bearing the Bis(3,5-dimethylpyrazol-1-yl)acetato Ligand. Inorganic Chemistry 47, 9624-9641 (2008). doi:10.1021/ic8000224.

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