Following infection, SARS-CoV-2’s leader protein nsp1 is the very first viral protein to be expressed. Interaction between SARS-CoV-2 nsp1 (purple), human ribosomal RNA (bright orange) and ribosomal proteins (mainly 40S, dark orange), with a highlight on nsp1’s KH motif (molecular representation in the zoomed-in view) mediating the interaction (PDB entry: 6ZOJ) Nsp1 takes over the […]
News
Stay up-to-date about what happens at Thorn Lab!
The Physics Christmas lecture at UHH has a long tradition, and this year Thorn Lab supported it with models and a diffraction experiment. It was presented by Prof. Dr. Arwen Pearson and Prof. Dr. Robin Sant(r)a, who successfully made the packed lecture hall sing carols, learn everything we can do with x-rays and cheer!
Everything you wanted to know about the SARS-CoV-2 E-Protein, which makes beautiful fivefold channels and is responsible for the curvature of virion particles - published ahead of print: https://doi.org/10.1080/0889311X.2023.2253735 Top view of the pentameric SARS-CoV-1 E-protein assembly with the ion channel at the centre (PDB: 5X29). Positively charged residues on the outside of the central […]
This question will be answered by Andrea Thorn and her students in the second round of the award-winning lecture "human made catastrophes".We are looking forward to the new semester and hopefully to a lot of fun and science! We are still looking for a show-runner: https://thorn-lab.com/job/student-assistant-m-f-d/
Our article "Structural biology of SARS-CoV-1/SARS-CoV-2 main protease" is now available for access! https://www.tandfonline.com/eprint/PYHA4HHGW54RIT3IQB8Q/full?target=10.1080/0889311X.2023.2222275
We are very excited that IUCr 2029 will be coming to Berlin!! Picture: Manfred Weiss and Tina Weigel presenting the Berlin bid for IUCr2029 at the general assembly at IUCr2023 in Melbourne
Every year, the Hamburg Government recognizes outstanding and innovative performances at its higher education institutions with The Hamburg Teaching Prize. Andrea was officially awarded the prize for 2023 last Friday in the Rathaus. It is a great honor and the lecture was a lot of fun (and serious science). https://www.min.uni-hamburg.de/ueber-die-fakultaet/aktuelles/2023/0712-lehrpreise-2022-2023.html
The new CCP4 reference paper is out and guess who is one of the co-authors 🙂https://onlinelibrary.wiley.com/iucr/doi/10.1107/S2059798323003595(Our standalone tool AUSPEX which utilizes ML to analyse diffraction data, is part of CCP4 since 2017)
Coronavirus accessory proteins were thought non-essential but this may not be true. Read about it in our newest article, summarizing what we learned! https://www.tandfonline.com/doi/full/10.1080/0889311X.2023.2173744
Thornlab was in television! In "nano" we explained how structural biology is used to combat the COVID-19 pandemic.Watch it here: https://www.3sat.de/wissen/nano/210202-sendung-nano-102.html (Picture on top by courtesy of ESRF Grenoble)