News

Andrea was very happy, after last year's break, to be back in Coldspring Harbor Labs to teach at the Crystallography Course there. The course was started decades ago on James Watson's and Jim Pflugrath's intiative, and Andrea was, 13 years ago, the youngest female to ever teach in its long history. Meanwhile, she is part […]

Our review on the SARS-CoV-2 spike protein is out! "Up, up, down, down: the structural biology of the SARS-CoV-2 spike protein and how it cheats the immune system" Read it at: https://www.tandfonline.com/doi/full/10.1080/0889311X.2024.2363756

Last Friday, Thorn Lab's first PhD student, Maximilian Edich, successfully defended his thesis. We all are very proud of Dr. Edich.

Together with Arwen Pearson, Andrea Thorn spoke about crystal structures last week at “Wissen vom Fass” in a pub in Hamburg. Science, fun and chocolate...

Andrea Thorn was interviewed by the German magazine "Laborjournal" about the future of AI in Cryo-EM! Read the whole story (in German) here: https://www.laborjournal.de/rubric/special/special/2024_04_02.php

Following infection, SARS-CoV-2’s leader protein nsp1 is the very first viral protein to be expressed. Interaction between SARS-CoV-2 nsp1 (purple), human ribosomal RNA (bright orange) and ribosomal proteins (mainly 40S, dark orange), with a highlight on nsp1’s KH motif (molecular representation in the zoomed-in view) mediating the interaction (PDB entry: 6ZOJ) Nsp1 takes over the […]

The Physics Christmas lecture at UHH has a long tradition, and this year Thorn Lab supported it with models and a diffraction experiment. It was presented by Prof. Dr. Arwen Pearson and Prof. Dr. Robin Sant(r)a, who successfully made the packed lecture hall sing carols, learn everything we can do with x-rays and cheer!

Everything you wanted to know about the SARS-CoV-2 E-Protein, which makes beautiful fivefold channels and is responsible for the curvature of virion particles - published ahead of print: https://doi.org/10.1080/0889311X.2023.2253735 Top view of the pentameric SARS-CoV-1 E-protein assembly with the ion channel at the centre (PDB: 5X29). Positively charged residues on the outside of the central […]

This question will be answered by Andrea Thorn and her students in the second round of the award-winning lecture "human made catastrophes".We are looking forward to the new semester and hopefully to a lot of fun and science! We are still looking for a show-runner: https://thorn-lab.com/job/student-assistant-m-f-d/

Our article "Structural biology of SARS-CoV-1/SARS-CoV-2 main protease" is now available for access! https://www.tandfonline.com/eprint/PYHA4HHGW54RIT3IQB8Q/full?target=10.1080/0889311X.2023.2222275